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Talphera - 14 Year Stock Price History | TLPH

Historical daily share price chart and data for Talphera since 2011 adjusted for splits and dividends. The latest closing stock price for Talphera as of August 29, 2025 is 0.54.
  • The all-time high Talphera stock closing price was 262.40 on July 22, 2013.
  • The Talphera 52-week high stock price is 1.19, which is 120.4% above the current share price.
  • The Talphera 52-week low stock price is 0.38, which is 29.6% below the current share price.
  • The average Talphera stock price for the last 52 weeks is 0.62.
For more information on how our historical price data is adjusted see the Stock Price Adjustment Guide.
  
Talphera Historical Annual Stock Price Data
Year Average Stock Price Year Open Year High Year Low Year Close Annual % Change
2025 0.5269 0.5900 0.7300 0.3900 0.5410 4.04%
2024 0.9443 0.7400 1.4700 0.5100 0.5200 -29.73%
2023 1.0096 2.2200 2.5900 0.4600 0.7400 -67.26%
2022 5.2817 12.2000 12.2000 1.7800 2.2600 -79.82%
2021 25.9810 25.0000 55.4000 9.8000 11.2000 -54.84%
2020 28.4198 41.4000 41.4000 15.2000 24.8000 -41.23%
2019 51.9698 49.6000 78.6000 33.2000 42.2000 -8.66%
2018 57.7219 41.0000 96.0000 34.0000 46.2000 13.79%
2017 55.1873 51.0000 110.0000 35.0000 40.6000 -21.92%
2016 65.6770 76.0000 86.2000 49.6000 52.0000 -32.47%
2015 93.8802 136.2000 182.6000 60.0000 77.0000 -42.79%
2014 180.3881 233.4000 260.6000 106.6000 134.6000 -40.50%
2013 159.8738 91.8000 262.4000 86.6000 226.2000 165.49%
2012 64.9912 38.6000 99.4000 38.6000 85.2000 121.88%
Sector Industry Market Cap Revenue
Medical Medical - Drug Manufacturing $0.011B $0.001B
Talphera Inc. is a specialty pharmaceutical company. It focused on the development and commercialization of therapies for use in medically supervised settings. The company's lead product candidate consists Niyad(TM). Talphera Inc., formerly known as AcelRx Pharmaceuticals Inc., is based in SAN MATEO, Calif.
Stock Name Country Market Cap PE Ratio
Chugai Pharmaceutical (CHGCY) Japan $72.041B 27.71
Zoetis (ZTS) United States $69.314B 25.14
Takeda Pharmaceutical (TAK) Japan $47.697B 9.73
Daiichi Sankyo, - (DSNKY) Japan $45.256B 23.19
BeOne Medicines - (ONC) Switzerland $33.543B 0.00
Sandoz Group AG (SDZNY) Switzerland $27.672B 0.00
Summit Therapeutics (SMMT) United States $17.605B 0.00
Merck (MKKGY) Germany $16.427B 10.68
Shionogi (SGIOY) Japan $14.649B 14.68
Neurocrine Biosciences (NBIX) United States $13.846B 41.30
United Therapeutics (UTHR) United States $13.747B 11.90
IPSEN (IPSEY) France $11.409B 0.00
Orion OYJ (ORINY) Finland $11.203B 27.00
Madrigal Pharmaceuticals (MDGL) United States $9.722B 0.00
Eisai (ESAIY) $8.913B 10.05
Corcept Therapeutics (CORT) United States $7.347B 61.70
Stevanato Group S.p.A (STVN) Italy $6.968B 41.09
Grifols, S.A (GRFS) Spain $6.855B 0.00
Ionis Pharmaceuticals (IONS) United States $6.796B 0.00
Ono Pharmaceutical (OPHLF) Japan $5.740B 19.71
Hikma Pharmaceuticals Plc (HKMPF) United Kingdom $5.436B 0.00
Soleno Therapeutics (SLNO) United States $3.596B 0.00
AMNEAL PHARMACEUTICALS, INC (AMRX) United States $3.003B 14.27
Crinetics Pharmaceuticals (CRNX) United States $2.919B 0.00
NewAmsterdam Pharma (NAMS) Netherlands $2.709B 0.00
Hypermarcas (HYPMY) Brazil $2.686B 20.19
Procaps Group, S.A (PROCF) Luxembourg $2.557B 0.00
Catalyst Pharmaceuticals (CPRX) United States $2.520B 8.44
Centessa Pharmaceuticals (CNTA) United Kingdom $2.248B 0.00
Ocular Therapeutix (OCUL) United States $2.124B 0.00
Dyne Therapeutics (DYN) United States $1.919B 0.00
BioCryst Pharmaceuticals (BCRX) United States $1.744B 0.00
Guardian Pharmacy Services (GRDN) United States $1.673B 0.00
Aurinia Pharmaceuticals Inc (AUPH) Canada $1.578B 23.51
Ardelyx (ARDX) United States $1.533B 0.00
Harrow (HROW) United States $1.443B 0.00
Avadel Pharmaceuticals (AVDL) Ireland $1.433B 0.00
Xeris Biopharma Holdings (XERS) United States $1.264B 0.00
Evotec AG (EVO) Germany $1.243B 0.00
Collegium Pharmaceutical (COLL) United States $1.222B 6.68
Enliven Therapeutics (ELVN) United States $1.201B 0.00
ARS Pharmaceuticals (SPRY) United States $1.148B 0.00
Cronos Group (CRON) Canada $0.996B 0.00
Amylyx Pharmaceuticals (AMLX) United States $0.836B 0.00
Akebia Therapeutics (AKBA) United States $0.833B 0.00
Elite Pharmaceuticals (ELTP) United States $0.735B 0.00
Theravance Biopharma (TBPH) United States $0.699B 57.83
Rigel Pharmaceuticals (RIGL) United States $0.697B 7.18
ProKidney (PROK) United States $0.695B 0.00
KalVista Pharmaceuticals (KALV) United States $0.678B 0.00
Organogenesis (ORGO) United States $0.653B 0.00
Relay Therapeutics (RLAY) United States $0.619B 0.00
Bioventus (BVS) United States $0.612B 14.80
Tourmaline Bio (TRML) United States $0.601B 0.00
Siga Technologies (SIGA) United States $0.601B 7.42
USANA Health Sciences (USNA) United States $0.583B 11.95
Xencor (XNCR) United States $0.580B 0.00
Nektar Therapeutics (NKTR) United States $0.568B 0.00
Savara (SVRA) United States $0.567B 0.00
Oruka Therapeutics (ORKA) United States $0.554B 0.00
Zevra Therapeutics (ZVRA) United States $0.509B 0.00
Esperion Therapeutics (ESPR) United States $0.448B 0.00
Nanobiotix S.A (NBTX) France $0.429B 0.00
Aquestive Therapeutics (AQST) United States $0.376B 0.00
Aldeyra Therapeutics (ALDX) United States $0.350B 0.00
Altimmune (ALT) United States $0.338B 0.00
Larimar Therapeutics (LRMR) United States $0.300B 0.00
Nature's Sunshine Products (NATR) United States $0.297B 19.37
4D Molecular Therapeutics (FDMT) United States $0.288B 0.00
Galectin Therapeutics (GALT) United States $0.274B 0.00
AleAnna (ANNA) United States $0.270B 0.00
Tonix Pharmaceuticals Holding (TNXP) United States $0.260B 0.00
Lexeo Therapeutics (LXEO) United States $0.259B 0.00
Korro Bio (KRRO) United States $0.217B 0.00
Ironwood Pharmaceuticals (IRWD) United States $0.214B 33.00
Lyell Immunopharma (LYEL) United States $0.213B 0.00
Aclaris Therapeutics (ACRS) United States $0.209B 0.00
Heron Therapeutics (HRTX) United States $0.207B 0.00
OmniAb (OABI) United States $0.196B 0.00
MediWound (MDWD) Israel $0.180B 0.00
Journey Medical (DERM) United States $0.176B 0.00
Innate Pharma SA (IPHYF) France $0.173B 0.00
China SXT Pharmaceuticals (SXTC) China $0.169B 0.00
MEI Pharma (MEIP) United States $0.160B 0.00
Achieve Life Sciences (ACHV) Canada $0.152B 0.00
Profound Medical (PROF) Canada $0.134B 0.00
Inhibikase Therapeutics (IKT) United States $0.134B 0.00
Avalo Therapeutics (AVTX) United States $0.122B 0.00
Protara Therapeutics (TARA) United States $0.120B 0.00
Avita Medical (RCEL) United States $0.116B 0.00
Corbus Pharmaceuticals Holdings (CRBP) United States $0.115B 0.00
Cassava Sciences (SAVA) United States $0.110B 0.00
Surrozen (SRZN) United States $0.104B 0.00
Wellgistics Health (WGRX) United States $0.103B 0.00
Dominari Holdings (DOMH) United States $0.099B 0.00
Champions Oncology (CSBR) United States $0.094B 21.25
Cardiol Therapeutics (CRDL) Canada $0.090B 0.00
VAXART, INC (VXRT) United States $0.089B 0.00
BioNxt Solutions (BNXTF) Canada $0.083B 0.00
Assertio Holdings (ASRT) United States $0.080B 0.00
Arch Biopartners (ACHFF) Canada $0.080B 0.00
Pyxis Oncology (PYXS) United States $0.079B 0.00
Context Therapeutics (CNTX) United States $0.075B 0.00
PMV Pharmaceuticals (PMVP) United States $0.074B 0.00
Unicycive Therapeutics (UNCY) United States $0.074B 0.00
Nutriband (NTRB) United States $0.072B 0.00
Gain Therapeutics (GANX) United States $0.072B 0.00
Liminatus Pharma (LIMN) United States $0.071B 0.00
Prelude Therapeutics (PRLD) United States $0.068B 0.00
Vivani Medical (VANI) United States $0.068B 0.00
Metagenomi (MGX) United States $0.065B 0.00
Karyopharm Therapeutics (KPTI) United States $0.062B 0.00
DURECT (DRRX) United States $0.060B 0.00
Inotiv (NOTV) United States $0.058B 0.00
PolyPid (PYPD) Israel $0.053B 0.00
Verrica Pharmaceuticals (VRCA) United States $0.053B 0.00
Cumberland Pharmaceuticals (CPIX) United States $0.052B 31.73
Rafael Holdings (RFL) United States $0.052B 0.00
Jupiter Neurosciences (JUNS) United States $0.051B 0.00
Fractyl Health (GUTS) United States $0.049B 0.00
FibroGen (FGEN) United States $0.048B 0.00
NRx Pharmaceuticals (NRXP) United States $0.046B 0.00
Plus Therapeutics (PSTV) United States $0.045B 0.00
Tempest Therapeutics (TPST) United States $0.044B 0.00
Telomir Pharmaceuticals (TELO) United States $0.043B 0.00
Klotho Neurosciences (KLTO) United States $0.043B 0.00
Century Therapeutics (IPSC) United States $0.042B 0.00
Acrivon Therapeutics (ACRV) United States $0.042B 0.00
ElectroCore (ECOR) United States $0.040B 0.00
Relmada Therapeutics (RLMD) United States $0.037B 0.00
Mural Oncology (MURA) Ireland $0.036B 0.00
SCYNEXIS (SCYX) United States $0.035B 0.00
Vivos Therapeutics (VVOS) United States $0.033B 0.00
Reviva Pharmaceuticals Holdings (RVPH) United States $0.031B 0.00
Iterum Therapeutics (ITRM) Ireland $0.030B 0.00
CASI Pharmaceuticals (CASI) China $0.028B 0.00
Mangoceuticals (MGRX) United States $0.025B 0.00
Enlivex Therapeutics (ENLV) Israel $0.025B 0.00
Cosmos Health (COSM) United States $0.024B 0.00
Natural Alternatives (NAII) United States $0.023B 0.00
Citius Pharmaceuticals (CTXR) United States $0.023B 0.00
Scienture Holdings (SCNX) United States $0.020B 0.00
Incannex Healthcare (IXHL) Australia $0.019B 0.00
Mannatech (MTEX) United States $0.018B 0.00
Ainos (AIMD) United States $0.018B 0.00
BioLineRx (BLRX) Israel $0.016B 0.00
Lipocine (LPCN) United States $0.016B 0.00
ProPhase Labs (PRPH) United States $0.014B 0.00
TherapeuticsMD (TXMD) United States $0.013B 0.00
MARKER THERAPEUTICS, INC (MRKR) United States $0.012B 0.00
Lyra Therapeutics (LYRA) United States $0.012B 0.00
BioVie (BIVI) United States $0.011B 0.00
ESSA Pharma (EPIX) Canada $0.011B 0.00
Phio Pharmaceuticals (PHIO) United States $0.011B 0.00
Aptorum Group (APM) United Kingdom $0.011B 0.00
Ernexa Therapeutics (ERNA) United States $0.010B 0.00
Traws Pharma (TRAW) United States $0.010B 0.02
Kiora Pharmaceuticals (KPRX) United States $0.010B 0.00
Heatwurx (PCSA) United States $0.010B 0.00
CERo Therapeutics Holdings (CERO) United States $0.009B 0.00
Carisma Therapeutics (CARM) United States $0.009B 0.00
TNF Pharmaceuticals (TNFA) United States $0.009B 0.00
Addex Therapeutics (ADXN) Switzerland $0.008B 0.00
VYNE Therapeutics (VYNE) United States $0.008B 0.00
TransCode Therapeutics (RNAZ) United States $0.008B 0.00
Biomerica (BMRA) United States $0.008B 0.00
NLS Pharmaceutics (NLSP) Switzerland $0.008B 0.00
Sonoma Pharmaceuticals (SNOA) United States $0.007B 0.00
Indaptus Therapeutics (INDP) United States $0.007B 0.00
XTL Biopharmaceuticals (XTLB) Israel $0.007B 0.00
Nuvilex (PMCB) United States $0.006B 0.00
Vyome Holdings (HIND) United States $0.006B 0.00
60 Degrees Pharmaceuticals (SXTP) United States $0.006B 0.00
Aditxt (ADTX) United States $0.005B 0.00
Alaunos Therapeutics (TCRT) United States $0.005B 0.00
Clearmind Medicine (CMND) Canada $0.005B 0.00
InMed Pharmaceuticals (INM) Canada $0.004B 0.00
Xenetic Biosciences (XBIO) United States $0.004B 0.00
Quoin Pharmaceuticals (QNRX) United States $0.004B 0.00
XORTX Therapeutics (XRTX) Canada $0.004B 0.00
CDT Equity (CDT) United States $0.004B 0.00
Jaguar Animal Health (JAGX) United States $0.004B 0.00
Shuttle Pharmaceuticals Holdings (SHPH) United States $0.004B 0.00
Redhill Biopharma (RDHL) Israel $0.003B 0.00
Qualigen Therapeutics (QLGN) United States $0.003B 0.00
Salarius Pharmaceuticals (SLRX) United States $0.003B 0.00
PainReform (PRFX) Israel $0.003B 0.00
SHINECO (SISI) China $0.002B 0.00
Galmed Pharmaceuticals (GLMD) Israel $0.002B 0.00
Universe Pharmaceuticals INC (UPC) China $0.002B 0.00
SciSparc (SPRC) Israel $0.001B 0.00
Indivior (INDV) United States $0.000B 13.64
4D Pharma (LBPS) United Kingdom $0.000B 0.00
Minerva Neurosciences (NERV) United States $0.000B 1.59
Patheon (PTHN) Netherlands $0.000B 0.00
RVL Pharmaceuticals (RVLP) United States $0.000B 0.00
Silence Therapeutics (SLN) United Kingdom $0.000B 0.00